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Oprm1tm2Kff
Targeted Allele Detail
Summary
Symbol: Oprm1tm2Kff
Name: opioid receptor, mu 1; targeted mutation 2, Brigitte L Kieffer
MGI ID: MGI:3698283
Gene: Oprm1  Location: Chr10:6708593-6988209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Alliance: Oprm1tm2Kff page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117867
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA stop codon was inserted into exon 3 and a floxed hygro cassette was inserted downstream of exon 3. This line has 96 nucleoties separating the premature stop codon and the downstream splice junction. The hygro was subsequently removed via cre mediated recombination. (J:117867)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  53 strains or lines available
References
Original:  J:117867 Contet C, et al., Knock-in mice reveal nonsense-mediated mRNA decay in the brain. Genesis. 2007 Jan;45(1):38-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory