Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Catsper4tm1Clph
Name:	cation channel, sperm associated 4; targeted mutation 1, David E Clapham
MGI ID:	MGI:3694354
Gene:	Catsper4  Location: Chr4:133939281-133954694 bp, - strand  Genetic Position: Chr4, 66.5 cM
Alliance:	Catsper4tm1Clph page

Germline Transmission:	Earliest citation of germline transmission: J:116406
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 5-8, including sequences encoding the putative pore region and part of the C-terminus of the protein, have been replaced by a neomycin resistance cassette. (J:116406)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Catsper4 Mutation:	26 strains or lines available

Original:	J:116406 Qi H, et al., All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23
All:	1 reference(s)