Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptf1atm2.1Mgn
Name:	pancreas specific transcription factor, 1a; targeted mutation 2.1, Mark A Magnuson
MGI ID:	MGI:3691484
Synonyms:	Ptf1aCitrine, Ptf1atm2Mgn, Ptf1aYFP
Gene:	Ptf1a  Location: Chr2:19450474-19452312 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Alliance:	Ptf1atm2.1Mgn page

Germline Transmission:	Earliest citation of germline transmission: J:115271
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted Mutation:    Insertion   Mutation details: This allele expresses citrine under the control of the endogenous promoter. Exons 1 and 2 were replaced by the citrine yellow variant of GFP inserted into exon 1, exon 2 and an frt-flanked hygro cassette via RMCE using the loxed cassette acceptor (LCA) allele-containing ES cells. (J:115271, J:135698)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

163 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:	30 strains or lines available

Original:	J:115271 Fujitani Y, et al., Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development. 2006 Nov;133(22):4439-50
All:	6 reference(s)