Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1.1Fia
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Faz I Ismat
MGI ID:	MGI:3689411
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1.1Fia page

Germline Transmission:	Earliest citation of germline transmission: J:114455
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted Mutation:    Insertion   Mutation details: The HA-tagged segment of human neurofibromatosis 1 cDNA encoding the 216 amino acid GTPase-activating protein-related domain remained in the locus after cre-mediated excision of the floxed neo. Western blot detected protein from the inserted sequence in mutants. (J:114455)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:114455 Ismat FA, et al., The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice. J Clin Invest. 2006 Sep;116(9):2378-84
All:	1 reference(s)