Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Esr2tm1Aghe
Name:	estrogen receptor 2 (beta); targeted mutation 1, A G H Ederveen
MGI ID:	MGI:3665335
Synonyms:	ERKObeta
Gene:	Esr2  Location: Chr12:76167193-76224033 bp, - strand  Genetic Position: Chr12, 33.52 cM, cytoband D1-D3
Alliance:	Esr2tm1Aghe page

Germline Transmission:	Earliest citation of germline transmission: J:111515
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A vector was designed to replace exon 2 and part of exon 3 with a neomycin resistance cassette. (J:111515)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr2 Mutation:	32 strains or lines available

Original:	J:111515 Van Cromphaut SJ, et al., Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms. J Bone Miner Res. 2003 Oct;18(10):1725-36
All:	1 reference(s)