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Cd4tm1Dim
Targeted Allele Detail
Summary
Symbol: Cd4tm1Dim
Name: CD4 antigen; targeted mutation 1, Diane Mathis
MGI ID: MGI:3665251
Synonyms: CD4L
Gene: Cd4  Location: Chr6:124841655-124865184 bp, - strand  Genetic Position: Chr6, 59.17 cM
Alliance: Cd4tm1Dim page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113263
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    Betagal cDNA was inserted into the initation codon in exon 2 by homologous recombination. (J:113263)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd4 Mutation:  82 strains or lines available
References
Original:  J:113263 Chan S, et al., Visualization of CD4/CD8 T cell commitment. J Exp Med. 1998 Dec 21;188(12):2321-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory