Pyytm1(cre)Hhzg
Targeted Allele Detail
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Symbol: |
Pyytm1(cre)Hhzg |
Name: |
peptide YY; targeted mutation 1, H Herzog |
MGI ID: |
MGI:3664105 |
Synonyms: |
Pyy- |
Gene: |
Pyy Location: Chr11:101997502-101998658 bp, - strand Genetic Position: Chr11, 65.48 cM
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Alliance: |
Pyytm1(cre)Hhzg page
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Greater bone mass in Pyytm1(cre)Hhzg/Pyytm1(cre)Hhzg mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:111480
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Pyytm1(cre)Hhzg expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pyy (MGI:99924) |
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Mutation details: A vector was designed to knock out gene function but allow the endogenous promoter to drive expression of cre-recombinase by inducible tetracycline promoter regulation.
(J:111480)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pyy
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pyy Mutation: |
9 strains or lines available
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Original: |
J:111480 Boey D, et al., Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity. Diabetologia. 2006 Jun;49(6):1360-1370 |
All: |
8 reference(s) |
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