Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd3etm1Cpt
Name:	CD3 antigen, epsilon polypeptide; targeted mutation 1, Cox Terhorst
MGI ID:	MGI:2155671
Synonyms:	epsilondeltaP
Gene:	Cd3e  Location: Chr9:44910038-44920925 bp, - strand  Genetic Position: Chr9, 24.84 cM
Alliance:	Cd3etm1Cpt page

Germline Transmission:	Earliest citation of germline transmission: J:54756
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-neomycin resistance cassette replaced the promoter region and exons 1, 2, and 3. (J:54756)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd3e Mutation:	47 strains or lines available

Original:	J:54756 Wang N, et al., Expression of a CD3 epsilon transgene in CD3 epsilon(null) mice does not restore CD3 gamma and delta expression but efficiently rescues T cell development from a subpopulation of prothymocytes. Int Immunol. 1998 Dec;10(12):1777-88
All:	11 reference(s)