Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tbx1tm1(Fgf8)Vite
Name:	T-box 1; targeted mutation 1, Francesca Vitelli
MGI ID:	MGI:3641283
Synonyms:	Tbx1Fgf8
Gene:	Tbx1  Location: Chr16:18399729-18409412 bp, - strand  Genetic Position: Chr16, Syntenic
Alliance:	Tbx1tm1(Fgf8)Vite page

Germline Transmission:	Earliest citation of germline transmission: J:110620
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Inserted expressed sequence) Mutation:    Insertion   Mutation details: A 0.8 kb Fgf8 cDNA encoding isoform 8b into exon 5 of the Tbx1 gene which encodes a portion of the essential T-box domain. (J:110620)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:	34 strains or lines available

Original:	J:110620 Vitelli F, et al., Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants. Dev Biol. 2006 Jul 15;295(2):559-70
All:	3 reference(s)