Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dnah11lrm3
Name:	dynein, axonemal, heavy chain 11; left-right mutant 3
MGI ID:	MGI:3640793
Gene:	Dnah11  Location: Chr12:117841717-118162778 bp, - strand  Genetic Position: Chr12, 63.25 cM
Alliance:	Dnah11lrm3 page

Strain of Origin:

BALB/cAnN

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This mutation, identified in an ENU mutagenesis screen, was determined to be an allele of this gene by its failure to complement the original situs inversus viscerum mutation. The molecular defect has been identified as a GA-to-GT transversion in the splice donor sequence at the end of exon 30, which results in splicing out of exon 30. (J:145068) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnah11 Mutation:	217 strains or lines available

Original:	J:145068 Ermakov A, et al., Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development. Dev Dyn. 2009 Feb 22;238(3):581-594
All:	2 reference(s)