Ecel1tm1Jroh
Targeted Allele Detail
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Symbol: |
Ecel1tm1Jroh |
Name: |
endothelin converting enzyme-like 1; targeted mutation 1, Jack Rohrer |
MGI ID: |
MGI:3629091 |
Synonyms: |
XCE- |
Gene: |
Ecel1 Location: Chr1:87075377-87084243 bp, - strand Genetic Position: Chr1, 44.06 cM, cytoband C5
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Alliance: |
Ecel1tm1Jroh page
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Congenital atelectasis in Ecel1tm1Jroh/Ecel1tm1Jroh lungs
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:56300
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The exon encoding the zinc-binding motif and the next two downstream exons were replaced with a neomycin resistance gene. RT-PCR analysis confirmed absence of transcript in mutant brain samples.
(J:56300)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ecel1 Mutation: |
41 strains or lines available
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Original: |
J:56300 Schweizer A, et al., Neonatal lethality in mice deficient in XCE, a novel member of the endothelin-converting enzyme and neutral endopeptidase family. J Biol Chem. 1999 Jul 16;274(29):20450-6 |
All: |
1 reference(s) |
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