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Adamts4tm1.1Lex
Targeted Allele Detail
Summary
Symbol: Adamts4tm1.1Lex
Name: ADAM metallopeptidase with thrombospondin type 1 motif 4; targeted mutation 1.1, Lexicon Genetics
MGI ID: MGI:3617790
Synonyms: ADAMTS-4-deltacat, ADAMTS4 delta-cat
Gene: Adamts4  Location: Chr1:171077990-171088206 bp, + strand  Genetic Position: Chr1, 79.28 cM
Alliance: Adamts4tm1.1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105138
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Cre mediated recombination was used to excise exon 4. (J:105138)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adamts4 Mutation:  48 strains or lines available
References
Original:  J:105138 Stanton H, et al., ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature. 2005 Mar 31;434(7033):648-52
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory