Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tgif1tm1Dwot
Name:	TGFB-induced factor homeobox 1; targeted mutation 1, David Wotton
MGI ID:	MGI:3617788
Synonyms:	Tgif-
Gene:	Tgif1  Location: Chr17:71151200-71160527 bp, - strand  Genetic Position: Chr17, 41.87 cM
Alliance:	Tgif1tm1Dwot page

Germline Transmission:	Earliest citation of germline transmission: J:105576
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Most of the second and third exons were removed and the GFP coding sequence was fused in-frame to codon 9. Northern blot failed to detect transcript in mutants. GFP was observed in a reciprocal expression pattern. (J:105576)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgif1 Mutation:	52 strains or lines available

Original:	J:105576 Bartholin L, et al., TGIF inhibits retinoid signaling. Mol Cell Biol. 2006 Feb;26(3):990-1001
All:	8 reference(s)