Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Del(8Nat1-Nat2)1Kss
Name:	deletion, Chr 8, Kim S Sugamori 1
MGI ID:	MGI:3612793
Synonyms:	Nat1/2(-), Nat1/Nat2tm1Kss, Nat1tm1Kss
Gene:	Del(8Nat1-Nat2)1Kss  Location: unknown  Genetic Position: Chr8, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:103885
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion, Intragenic deletion   Del(8Nat1-Nat2)1Kss involves 2 genes/genome features (Nat1, Nat2) View all   Mutation details: A neomycin resistance gene was inserted to delete ~11 kb of sequence, including the entire coding region of Nat1 and most of the coding region of Nat2. RT-PCR failed to detect transcript of either gene in mutants. (J:103885)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(8Nat1-Nat2)1Kss Mutation:	0 strains or lines available

Original:	J:103885 Sugamori KS, et al., Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice. Mol Pharmacol. 2003 Jul;64(1):170-9
All:	6 reference(s)