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Mtf1tm2Wsc
Targeted Allele Detail
Nomenclature
Symbol: Mtf1tm2Wsc
Name: metal response element binding transcription factor 1; targeted mutation 2, Walter Schaffner
MGI ID: MGI:3609186
Synonyms: Mtf1loxP
Gene: Mtf1  Location: Chr4:124802549-124849800 bp, + strand  Genetic Position: Chr4, 57.91 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:102512
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to flank exons 3 and 4, encoding four of the six zinc fingers of the DNA-binding domain, with loxP sites. (J:102512)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mtf1 Mutation:  11 strains or lines available
References
Original:  J:102512 Wimmer U, et al., Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res. 2005;33(18):5715-27
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory