Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mtf1tm2Wsc
Name:	metal response element binding transcription factor 1; targeted mutation 2, Walter Schaffner
MGI ID:	MGI:3609186
Synonyms:	Mtf1loxP
Gene:	Mtf1  Location: Chr4:124696342-124743593 bp, + strand  Genetic Position: Chr4, 57.91 cM, cytoband D1
Alliance:	Mtf1tm2Wsc page

Germline Transmission:	Earliest citation of germline transmission: J:102512
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to flank exons 3 and 4, encoding four of the six zinc fingers of the DNA-binding domain, with loxP sites. (J:102512)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mtf1 Mutation:	38 strains or lines available

Original:	J:102512 Wimmer U, et al., Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res. 2005;33(18):5715-27
All:	1 reference(s)