Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dicer1tm1.1Bdh
Name:	dicer 1, ribonuclease type III; targeted mutation 1.1, Brian D Harfe
MGI ID:	MGI:3589209
Synonyms:	Dicerfloxdelta, Diverdelta
Gene:	Dicer1  Location: Chr12:104654001-104718211 bp, - strand  Genetic Position: Chr12, 54.83 cM, cytoband E-F1
Alliance:	Dicer1tm1.1Bdh page

Germline Transmission:	Earliest citation of germline transmission: J:100475
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Crossing Dicer1tm1Bdh mice with mice expressing cre in the germline resulted in the loss of the exon encoding most of the second RNaseIII domain. (J:100475)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dicer1 Mutation:	94 strains or lines available

Original:	J:100475 Harfe BD, et al., The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10898-903
All:	13 reference(s)