Rag1tm1(cre)Thr
Targeted Allele Detail
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Symbol: |
Rag1tm1(cre)Thr |
Name: |
recombination activating 1; targeted mutation 1, Terence H Rabbitts |
MGI ID: |
MGI:3584018 |
Synonyms: |
Rag1-cre |
Gene: |
Rag1 Location: Chr2:101468627-101479846 bp, - strand Genetic Position: Chr2, 53.88 cM
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Alliance: |
Rag1tm1(cre)Thr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:86869
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Rag1tm1(cre)Thr expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Rag1 (MGI:97848) |
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Mutation details: Cre cDNA was cloned in-frame with the endogenous coding sequence, along with an SV40 pA signal and a neomycin resistance cassette.
(J:86869)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Rag1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rag1 Mutation: |
120 strains or lines available
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Original: |
J:86869 McCormack MP, et al., The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development. Mol Cell Biol. 2003 Dec;23(24):9003-13 |
All: |
34 reference(s) |
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