Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hprt1tm1Pobe
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Philipp Oberdoerffer
MGI ID:	MGI:3582525
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm1Pobe page

Germline Transmission:	Earliest citation of germline transmission: J:98881
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector designed to insert a U6-STOP-shA1 cassette into the locus to allow ubiquitous expression of shA1-mediated RNAi upon Cre-mediated recombination. (J:98881)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:98881 Oberdoerffer P, et al., Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages. Mol Cell Biol. 2005 May;25(10):3896-905
All:	1 reference(s)