Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Recql5tm1Glu
Name:	RecQ protein-like 5; targeted mutation 1, Guangbin Luo
MGI ID:	MGI:3577099
Synonyms:	M2
Gene:	Recql5  Location: Chr11:115783421-115824303 bp, - strand  Genetic Position: Chr11, 80.91 cM, cytoband E2
Alliance:	Recql5tm1Glu page

Germline Transmission:	Earliest citation of germline transmission: J:97667
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted into intron 3 and a loxP flanked PGK-neo was inserted into intron 4. Crossing with mice expressing Cre in the germline removed the floxed neo. (J:97667)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Recql5 Mutation:	53 strains or lines available

Original:	J:97667 Hu Y, et al., Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers. Mol Cell Biol. 2005 May;25(9):3431-42
All:	1 reference(s)