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Rb1tm2Htr
Targeted Allele Detail
Summary
Symbol: Rb1tm2Htr
Name: RB transcriptional corepressor 1; targeted mutation 2, Hein te Riele
MGI ID: MGI:3530301
Synonyms: Rb1tm2Nki, RbHyg
Gene: Rb1  Location: Chr14:73430298-73563446 bp, - strand  Genetic Position: Chr14, 38.73 cM, cytoband D3
Alliance: Rb1tm2Htr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90477
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A hygromycin cassette was inserted into the Bgl2 restriction site in Rb1 exon 19. (J:90477)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rb1 Mutation:  106 strains or lines available
References
Original:  J:90477 te Riele H, et al., Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5128-32
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory