Pdcd1lg2tm1Lex
Targeted Allele Detail
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| Symbol: |
Pdcd1lg2tm1Lex |
| Name: |
programmed cell death 1 ligand 2; targeted mutation 1, Lexicon Genetics |
| MGI ID: |
MGI:3529315 |
| Synonyms: |
PD-L2CKO |
| Gene: |
Pdcd1lg2 Location: Chr19:29388319-29448561 bp, + strand Genetic Position: Chr19, 23.93 cM, cytoband C2-C3
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| Alliance: |
Pdcd1lg2tm1Lex page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:126829
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S/SvEvBrd
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| Project Collection: |
Lexicon
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: By homologous recombination, a loxP site was inserted 5' of exon 2, followed by a NeoR cassette and a 3' loxP site. The resulting mutant mice were used to create Pdcd1lg2tm1.1Lex.
(J:126829)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pdcd1lg2 Mutation: |
23 strains or lines available
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| Original: |
J:126829 Carter LL, et al., PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2007 Jan;182(1-2):124-34 |
| All: |
1 reference(s) |
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Analysis Tools
