Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Slc2a4tm1Mch
Name:	solute carrier family 2 (facilitated glucose transporter), member 4; targeted mutation 1, Maureen J Charron
MGI ID:	MGI:2149725
Synonyms:	GLUT-4 null
Gene:	Slc2a4  Location: Chr11:69833365-69839014 bp, - strand  Genetic Position: Chr11, 42.93 cM, cytoband C-E1
Alliance:	Slc2a4tm1Mch page

Germline Transmission:	Earliest citation of germline transmission: J:49328
Parent Cell Line:	WW6 (ES Cell)
Strain of Origin:	STOCK 129/Sv and C57BL/6J and SJL

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance cassette was inserted into exon 10 of the gene, disrupting expression. Loss of expression was shown by Northern and Western blots of skeletal muscle. (J:49328)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc2a4 Mutation:	35 strains or lines available

Original:	J:49328 Katz EB, et al., Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4 [see comments]. Nature. 1995 Sep 14;377(6545):151-5
All:	25 reference(s)