Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Gata4tm1.2Wtp
Name:	GATA binding protein 4; targeted mutation 1.2, William T Pu
MGI ID:	MGI:3526856
Synonyms:	G4D, Gata4-, Gata4delta, Gata4deltaex2
Gene:	Gata4  Location: Chr14:63436371-63509141 bp, - strand  Genetic Position: Chr14, 33.24 cM
Alliance:	Gata4tm1.2Wtp page

Germline Transmission:	Earliest citation of germline transmission: J:94637
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Gata4tm1Wtp mice were crossed with Tg(EIIa-cre)C5379Lmgd to excise the floxed region including exon 2. Detailed analysis showed this to be a null allele. (J:94637)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata4 Mutation:	36 strains or lines available

Original:	J:94637 Pu WT, et al., GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Dev Biol. 2004 Nov 1;275(1):235-44
All:	13 reference(s)