Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lalbatm1.1(LALBA)Asty
Name:	lactalbumin, alpha; targeted mutation 1.1, Alexander Stacey
MGI ID:	MGI:3513837
Synonyms:	Alpha-lach, HMAL
Gene:	Lalba  Location: Chr15:98378281-98380602 bp, - strand  Genetic Position: Chr15, 54.48 cM
Alliance:	Lalbatm1.1(LALBA)Asty page

Germline Transmission:	Earliest citation of germline transmission: J:16483
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Mutation details: ES cells containing the Lalbatm1Asty mutation were further targeted with a vector designed to replace the HPRT minigene with human LALBA cDNA. (J:16483)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lalba Mutation:	8 strains or lines available

Original:	J:16483 Stacey A, et al., Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice. Mol Cell Biol. 1994 Feb;14(2):1009-16
All:	2 reference(s)