Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Sncbtm1Sud
Name:	synuclein, beta; targeted mutation 1, Thomas C Sudhof
MGI ID:	MGI:3487296
Synonyms:	BSF
Gene:	Sncb  Location: Chr13:54906673-54914408 bp, - strand  Genetic Position: Chr13, 29.28 cM
Alliance:	Sncbtm1Sud page

Germline Transmission:	Earliest citation of germline transmission: J:93544
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to flank the first coding exon (exon 2) with loxP sites and to insert an FRT-flanked neomycin resistance gene into intron 3. Crossing with mice expressing FLP recombinase excised the neo. (J:93544)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sncb Mutation:	18 strains or lines available

Original:	J:93544 Chandra S, et al., Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14966-71
All:	1 reference(s)