Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nr5a1tm1Jmi
Name:	nuclear receptor subfamily 5, group A, member 1; targeted mutation 1, Jeffrey Milbrandt
MGI ID:	MGI:1931426
Synonyms:	SF1 -
Gene:	Nr5a1  Location: Chr2:38582668-38604554 bp, - strand  Genetic Position: Chr2, 24.42 cM
Alliance:	Nr5a1tm1Jmi page

Germline Transmission:	Earliest citation of germline transmission: J:35577
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Replacement of ~100 bp of genomic sequence with a neomycin cassette. This region corresponded to the coding sequences for one of the zinc finger domains. (J:35577)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr5a1 Mutation:	30 strains or lines available

Original:	J:35577 Sadovsky Y, et al., Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):10939-43
All:	2 reference(s)