Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nkx3-1tm1Siz
Name:	NK3 homeobox 1; targeted mutation 1, Seigo Izumo
MGI ID:	MGI:1928655
Synonyms:	Nkx3.1 -
Gene:	Nkx3-1  Location: Chr14:69428141-69432107 bp, + strand  Genetic Position: Chr14, 36.02 cM
Alliance:	Nkx3-1tm1Siz page

Germline Transmission:	Earliest citation of germline transmission: J:64981
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, encoding the homeodomain and NK-2 specific domain were deleted and replaced by a neomycin cassette. (J:64981)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx3-1 Mutation:	39 strains or lines available

Original:	J:64981 Tanaka M, et al., Nkx3.1, a murine homolog of drosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn. 2000 Oct;219(2):248-60
All:	1 reference(s)