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Hoxb1tm7Mrc
Targeted Allele Detail
Summary
Symbol: Hoxb1tm7Mrc
Name: homeobox B1; targeted mutation 7, Mario R Capecchi
MGI ID: MGI:3046794
Synonyms: Hoxb1C
Gene: Hoxb1  Location: Chr11:96256578-96259082 bp, + strand  Genetic Position: Chr11, 59.86 cM
Alliance: Hoxb1tm7Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91364
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe entire coding region was flanked with lox511 sites following the excision of a floxed neo by crossing with deleter strain expressing Flp in the germ line. Southern blot confirmed recombination. (J:91364)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb1 Mutation:  24 strains or lines available
References
Original:  J:91364 Arenkiel BR, et al., Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Genes Dev. 2004 Jul 1;18(13):1539-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory