Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prnpa
Name:	prion protein; a
MGI ID:	MGI:3045029
Gene:	Prnp  Location: Chr2:131751848-131780349 bp, + strand  Genetic Position: Chr2, 64.07 cM
Alliance:	Prnpa page

Strain of Origin:

NZW

Allele Type:    Spontaneous Mutation:    Nucleotide substitutions   Mutation details: The protein product for this allele has a Leucine (L) at amino acid residue 108 and a Threonine (T) at amino acid residue 189. DNA from the NZW mouse was originally sequenced. Other mouse strains with the same allele are: RIIS/J, C57BL/6J, CAST/Ei, MOLF/Ei, and MA/MyJ. (J:8918)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prnp Mutation:	150 strains or lines available

Original:	J:8918 Westaway D, et al., Distinct prion proteins in short and long scrapie incubation period mice. Cell. 1987 Nov 20;51(4):651-62
All:	5 reference(s)