Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Efnb1tm1.1Sor
Name:	ephrin B1; targeted mutation 1.1, Philippe Soriano
MGI ID:	MGI:3039290
Synonyms:	ephrin-B1null
Gene:	Efnb1  Location: ChrX:98179736-98192597 bp, + strand  Genetic Position: ChrX, 43.22 cM, cytoband D
Alliance:	Efnb1tm1.1Sor page

Germline Transmission:	Earliest citation of germline transmission: J:89008
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removes the floxed exons 2-5 in Ephb1tm1Sor, leaving a PGK-neo-bpA cassette flanked by FRT sites. Western blot of embryo lysates confirmed absence of the endogenous protein. (J:89008, J:143845)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	60 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efnb1 Mutation:	15 strains or lines available

Original:	J:89008 Davy A, et al., Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004 Mar 1;18(5):572-83
All:	13 reference(s)