Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Vegfatm1.1Nagy
Name:	vascular endothelial growth factor A; targeted mutation 1.1, Andras Nagy
MGI ID:	MGI:1889787
Synonyms:	VEGF-Ahyper, Vegfhi, Vegf-IRES-lacZ, VEGFLacZ, VEGFlacZ-KI, VEGF-LacZ-KI-delta-neo
Gene:	Vegfa  Location: Chr17:46327919-46343295 bp, - strand  Genetic Position: Chr17, 22.79 cM
Alliance:	Vegfatm1.1Nagy page

Germline Transmission:	Earliest citation of germline transmission: J:56939
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: This allele is a derivative of Vegftm1Nagy where the PGK-neomycin resistance cassette has been deleted via a Cre/loxP recombination event. The allele expresses a bicistronic message encoding VEGF and LacZ proteins. (J:56939)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	119 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vegfa Mutation:	37 strains or lines available

Original:	J:56939 Miquerol L, et al., Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol. 1999 Aug 15;212(2):307-22
All:	34 reference(s)