Myod1tm1Glh
Targeted Allele Detail
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| Symbol: |
Myod1tm1Glh |
| Name: |
myogenic differentiation 1; targeted mutation 1, David J Goldhamer |
| MGI ID: |
MGI:3027182 |
| Synonyms: |
CEneo |
| Gene: |
Myod1 Location: Chr7:46025898-46028516 bp, + strand Genetic Position: Chr7, 30.03 cM
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| Alliance: |
Myod1tm1Glh page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:87370
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| Parent Cell Line: |
GS1 (ES Cell)
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| Strain of Origin: |
129/Sv
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| Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The core enhancer, located approximately 20 kb upstream of the start of transcription, was replaced with a floxed neomycin selection cassette inserted by homologous recombination. Transcript levels in homozygous embryos and adults were determined to be less than 20% those of wild-type.
(J:87370)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Myod1 Mutation: |
23 strains or lines available
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| Original: |
J:87370 Chen JC, et al., The core enhancer is essential for proper timing of MyoD activation in limb buds and branchial arches. Dev Biol. 2004 Jan 15;265(2):502-12 |
| All: |
1 reference(s) |
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Analysis Tools
