Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hbbs2
Name:	hemoglobin beta chain complex; s2
MGI ID:	MGI:1858117
Gene:	Hbb  Location: unknown  Genetic Position: Chr7, Syntenic

Strain of Origin:

C57BL/6

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: Analysis of the amino acid sequence of the variant beta-globin revealed that the valine at position 60 was changed to glutamic acid. The authors proposed that the mutational mechanism for such an alteration is an A-to-T transversion in codon 60. it is unclear whether the mutation was in the Hbb-b1 gene or the Hbb-b2 gene. (J:8002)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hbb Mutation:	47 strains or lines available

Original:	J:8002 Lewis SE, et al., A mutation in the beta-globin gene detected in the progeny of a female mouse treated with ethylnitrosourea. Proc Natl Acad Sci U S A. 1985 Sep;82(17):5829-31
All:	3 reference(s)