Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Portm1Wolf
Name:	cytochrome p450 oxidoreductase; targeted mutation 1, C Roland Wolf
MGI ID:	MGI:2656919
Synonyms:	CPRlox, HRN, PORlox
Gene:	Por  Location: Chr5:135698894-135764180 bp, + strand  Genetic Position: Chr5, 75.34 cM, cytoband G1
Alliance:	Portm1Wolf page

Germline Transmission:	Earliest citation of germline transmission: J:82951
Parent Cell Line:	GK129 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was introduced into intron 4 and a single loxP site was introduced into intron 15 via homologous recombination. (J:82951)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Por Mutation:	78 strains or lines available

Original:	J:82951 Henderson CJ, et al., Inactivation of the hepatic cytochrome p450 system by conditional deletion of hepatic cytochrome p450 reductase. J Biol Chem. 2003 Apr 11;278(15):13480-6
All:	10 reference(s)