Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Paxip1tm1Gdr
Name:	PAX interacting (with transcription-activation domain) protein 1; targeted mutation 1, Gregory R Dressler
MGI ID:	MGI:2653321
Synonyms:	PTIP-
Gene:	Paxip1  Location: Chr5:27945078-27996689 bp, - strand  Genetic Position: Chr5, 13.23 cM, cytoband A3
Alliance:	Paxip1tm1Gdr page

Germline Transmission:	Earliest citation of germline transmission: J:82319
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence encompassing exons 1 through 3 was replaced with a neo cassette inserted by homologous recombination. No protein was detected in homozygous mutant embyros by Western blot analysis. (J:82319)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Paxip1 Mutation:	46 strains or lines available

Original:	J:82319 Cho EA, et al., BRCT domain-containing protein PTIP is essential for progression through mitosis. Mol Cell Biol. 2003 Mar;23(5):1666-73
All:	5 reference(s)