Hprt1tm1(ACTB-Epor)Unc
Targeted Allele Detail
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| Symbol: |
Hprt1tm1(ACTB-Epor)Unc |
| Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, University of North Carolina |
| MGI ID: |
MGI:2450106 |
| Synonyms: |
tEpoR |
| Gene: |
Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
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| Alliance: |
Hprt1tm1(ACTB-Epor)Unc page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:81859
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutations: |
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Insertion, Intragenic deletion
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Hprt1tm1(ACTB-Epor)Unc expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Epor (MGI:95408) |
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Mutation details: A targeting construct containing human beta actin promoter sequence adjoined to a cDNA fragment encoding a truncated erythropoietin receptor lacking 91 carboxy terminal amino acids was inserted at the endogenous locus via homologous recombination. An Hprt rescue technique using E14TG2a ES cells was used for selection to achieve a single copy insertion.
(J:81859)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Hprt1 Mutation: |
1273 strains or lines available
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| Original: |
J:81859 Kirby SL, et al., Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9402-7 |
| All: |
2 reference(s) |
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Analysis Tools
