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Myf5tm3Thbr
Targeted Allele Detail
Summary
Symbol: Myf5tm3Thbr
Name: myogenic factor 5; targeted mutation 3, Thomas Braun
MGI ID: MGI:2449228
Synonyms: Myf-5loxP
Gene: Myf5  Location: Chr10:107318769-107321995 bp, - strand  Genetic Position: Chr10, 55.95 cM
Alliance: Myf5tm3Thbr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63517
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA single loxP site was inserted 5' to exon 1 and a loxP-flanked neomycin and thymidine kinase selection cassette was inserted in intron 1. The selection cassette was removed in ES cells by transient Cre recombinase expression prior to the production of mice. The final allele has loxP sites flanking exon 1. (J:63517)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myf5 Mutation:  17 strains or lines available
References
Original:  J:63517 Kaul A, et al., Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5 mutant mice. Cell. 2000 Jul 7;102(1):17-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory