Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cer1tm1.1Rph
Name:	cerberus 1, DAN family BMP antagonist; targeted mutation 1.1, Richard P Harvey
MGI ID:	MGI:2445492
Synonyms:	Cer1lacZ
Gene:	Cer1  Location: Chr4:82799988-82803385 bp, - strand  Genetic Position: Chr4, 39.4 cM
Alliance:	Cer1tm1.1Rph page

Germline Transmission:	Earliest citation of germline transmission: J:62081
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The floxed hygromycin gene that replaced the first coding exon was excised from Cer1tm1Rph via in vivo cre mediated recombination. The inserted lacZ gene remained in place of sequence encoding the initiator methionine, signal sequence, prosequence, and the first cysteine of the cystine knot. The expression pattern of lacZ was similar to that of the endogenous gene. (J:62081)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cer1 Mutation:	11 strains or lines available

Original:	J:62081 Stanley EG, et al., Targeted insertion of a lacZ reporter gene into the mouse Cer1 locus reveals complex and dynamic expression during embryogenesis [letter]. Genesis. 2000 Apr;26(4):259-64
All:	1 reference(s)