Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hprt1b-m1
Name:	hypoxanthine phosphoribosyltransferase 1; hypoxanthine guanine phosphoribosyl transferase B, mutation 1
MGI ID:	MGI:1857297
Synonyms:	Hprt-bm1
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1b-m1 page

Germline Transmission:	Earliest citation of germline transmission: J:15485
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Transgene Type:    Transgenic (Null/knockout) Mutation:    Insertion     A retroviral sequence was inserted into intron 1 in ES cells carrying Hprtb. (J:3354)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:15485 Kuehn MR, et al., A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice. Nature. 1987 Mar 19-25;326(6110):295-8
All:	7 reference(s)