Phenotypes Associated with This Genotype

Genotype
MGI:8322162

• Allelic Composition: Snhg5^em1Kabo/Snhg5^em1Kabo; Pkd1^tm2Som/Pkd1^tm2Som; Tg(Pkhd1-cre)1Igr/0
• Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

polycystic kidney ( J:379194 )

• kidneys exhibit a mild exacerbation of cystic disease seen in single Pkd1 conditional mice, with modestly higher mean kidney weight-to-body weight ratio, cyst index, and cyst counts that do not reach significance

increased kidney weight ( J:379194 )

• kidney weight-to-body-weight ratio is modestly higher than in single Pkd1conditional mutant mice but it does not reach significance

renal/urinary system

polycystic kidney ( J:379194 )

• kidneys exhibit a mild exacerbation of cystic disease seen in single Pkd1 conditional mice, with modestly higher mean kidney weight-to-body weight ratio, cyst index, and cyst counts that do not reach significance

increased kidney weight ( J:379194 )

• kidney weight-to-body-weight ratio is modestly higher than in single Pkd1conditional mutant mice but it does not reach significance