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Phenotypes Associated with This Genotype
Genotype
MGI:7780191
Allelic
Composition		 Lcn9em2Osb/Lcn9em2Osb
Genetic
Background		 involves: C57BL/6NCrSlc * DBA/2CrSlc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lcn9em2Osb mutation (1 available); any Lcn9 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reduced male fertility ( J:340906 )
• male fertility is reduced
• however, no apparent defects in sperm morphology and epididymis histology are seen
impaired binding of sperm to zona pellucida ( J:340906 )
• in IVF, spermatozoa efficiently fertilize cumulus-intact oocytes but barely bind to the cumulus-free zona pellucida

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory