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Phenotypes Associated with This Genotype
Genotype
MGI:7779934
Allelic
Composition
Gigyf1em1Xio/Gigyf1em1Xio
Gad2tm2(cre)Zjh/Gad2+
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gad2tm2(cre)Zjh mutation (3 available); any Gad2 mutation (59 available)
Gigyf1em1Xio mutation (0 available); any Gigyf1 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit an impairment in cognitive performance in the novel object recognition test
• however, mice do not show changes in sociability, social novelty, rearing, marble burying, elevated plus maze, or T-maze
• mice exhibit elevated anxiety levels, spending less time in centers of the open field
• mice exhibit reduced grooming behavior


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory