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Phenotypes Associated with This Genotype
Genotype
MGI:7778319
Allelic
Composition		 Trim71tm1695Arte/Trim71tm1695Arte
Tg(tetO-cre)1Jaw/0
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic
Background		 B6.Cg-Gt(ROSA)26Sortm1(rtTA*M2)Jae Trim71tm1695Arte Tg(tetO-cre)1Jaw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(rtTA*M2)Jae mutation (32 available); any Gt(ROSA)26Sor mutation (1062 available)
Tg(tetO-cre)1Jaw mutation (7 available)
Trim71tm1695Arte mutation (0 available); any Trim71 mutation (168 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal neural tube morphology ( J:335575 )
• doxycycline treatment at E5.5 results in completely penetrant neural tube defects at E12.5
• however, doxycycline treatment at P0.5 results in normal brain development

nervous system
abnormal neural tube morphology ( J:335575 )
• doxycycline treatment at E5.5 results in completely penetrant neural tube defects at E12.5
• however, doxycycline treatment at P0.5 results in normal brain development

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory