Phenotypes Associated with This Genotype

Genotype
MGI:7705898

• Allelic Composition: Lse/Lse⁺; Twist1^tm1Bhr/Twist1⁺
• Genetic Background: involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:338204 )

craniofacial

cleft palate ( J:338204 )

• apparent posterior cleft at E18.5 in microCT scans

cleft soft palate ( J:338204 )

• epiglottal soft-tissue cleft in the posterior soft palate

lowered ear position ( J:338204 )

• at E18.5

behavior/neurological

absent gastric milk in neonates ( J:338204 )

• at P0

limbs/digits/tail

polydactyly ( J:338204 )

• hindlimb polydactyly

growth/size/body

cleft palate ( J:338204 )

• apparent posterior cleft at E18.5 in microCT scans

cleft soft palate ( J:338204 )

• epiglottal soft-tissue cleft in the posterior soft palate

lowered ear position ( J:338204 )

• at E18.5

distended abdomen ( J:338204 )

• air-filled swollen abdomens at P0

hearing/vestibular/ear

lowered ear position ( J:338204 )

• at E18.5

digestive/alimentary system

cleft palate ( J:338204 )

• apparent posterior cleft at E18.5 in microCT scans

cleft soft palate ( J:338204 )

• epiglottal soft-tissue cleft in the posterior soft palate