Phenotypes Associated with This Genotype

Genotype
MGI:7660551

• Allelic Composition: rd25/rd25
• Genetic Background: B6.Cg-rd25/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

retina rod cell degeneration ( J:349874 )

retina degeneration ( J:349874 )

• Although homozygotes have a normal retina at 3 months of age they begin to display retinal degeneration by 5 months of age and have 30-40% photoreceptor loss at 10 months of age

abnormal rod electrophysiology ( J:349874 )

• homozygotes have normal rod ERG responses at 3 months of age, but diminished at 5 and 10 months of age; the cone ERG responses are not much changed in this time frame

nervous system

retina rod cell degeneration ( J:349874 )