About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:7659222
Allelic
Composition		 Il11tm2.1Moto/Il11tm2.1Moto
Tg(Adipoq-cre)1Evdr/0
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il11tm2.1Moto mutation (0 available); any Il11 mutation (21 available)
Tg(Adipoq-cre)1Evdr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
adipose tissue phenotype ( J:345337 )
N
• mice show normal amount of white adipose tissue

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:345337 )
N
• mice do not develop insulin resistance or glucose intolerance and show normal serum IL-11 and osteocalcin levels

skeleton
skeleton phenotype ( J:345337 )
N
• mice show no differences in cortical or cancellous bone mineral density

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory