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Phenotypes Associated with This Genotype
Genotype
MGI:7643474
Allelic
Composition		 Psmd11tm1.1Qit/Psmd11tm1.1Qit
Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa/Gt(ROSA)26Sor+
Tg(ACTFLPe)9205Dym/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-Cre/ERT2)Dsa mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
Psmd11tm1.1Qit mutation (0 available); any Psmd11 mutation (42 available)
Tg(ACTFLPe)9205Dym mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased apoptosis ( J:301736 )
• mouse embryonic fibroblasts (MEFs) from E14.5 embryos treated with 4-hydroxytamoxifen to induce deletion of the floxed Psmd11 allele exhibit increased apoptosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory