Phenotypes Associated with This Genotype

Genotype
MGI:7628244

• Allelic Composition: Ints15^em1Takas/Ints15⁺
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal eye morphology ( J:337973 )

• 3% of mice show local chorioretinal atrophy

• however, no retinal folds, cataracts, corneal opacity, iris anomaly, Peters anomaly or microphthalmos are observed

abnormal retina blood vessel morphology ( J:337973 )

• 26% of mice exhibit narrowing of retinal vessels

• 7% of mice show sheathing of retinal vessels

• however, no retinal hemangioma is observed

abnormal optic disk morphology ( J:337973 )

• 14% of mice show a pigmentation phenotype in the optic nerve head

• however, no optic nerve head anomaly is observed

abnormal eye development ( J:337973 )

persistence of hyaloid vascular system ( J:337973 )

• 55% of mice show persistence of ocular fetal vasculature (PFV) on the optic nerve head

cardiovascular system

abnormal retina blood vessel morphology ( J:337973 )

• 26% of mice exhibit narrowing of retinal vessels

• 7% of mice show sheathing of retinal vessels

• however, no retinal hemangioma is observed

nervous system

abnormal optic disk morphology ( J:337973 )

• 14% of mice show a pigmentation phenotype in the optic nerve head

• however, no optic nerve head anomaly is observed