Phenotypes Associated with This Genotype

Genotype
MGI:7614267

• Allelic Composition: Tg(Myh6-Cand1)1Zpan/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased response of heart to induced stress ( J:345515 )

• mice exhibit alleviation of transverse aortic constriction (TAC)-induced cardiac hypertrophy, showing improved left ventricular ejection fraction, fractional shortening, and left ventricle internal dimension at end-diastole (LVIDs) and left ventricle internal dimension at systole (LVIDd), ratios of heart weight to body weight, heart weight to tibia length, and lung weight to body weight, and heart size and abrogated increases in areas of cell size and cardiac fibrosis

homeostasis/metabolism

decreased response of heart to induced stress ( J:345515 )

• mice exhibit alleviation of transverse aortic constriction (TAC)-induced cardiac hypertrophy, showing improved left ventricular ejection fraction, fractional shortening, and left ventricle internal dimension at end-diastole (LVIDs) and left ventricle internal dimension at systole (LVIDd), ratios of heart weight to body weight, heart weight to tibia length, and lung weight to body weight, and heart size and abrogated increases in areas of cell size and cardiac fibrosis