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Phenotypes Associated with This Genotype
Genotype
MGI:7612229
Allelic
Composition		 Mldhrtm1Zhgn/Mldhrtm1Zhgn
Tg(GFAP-cre)25Mes/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mldhrtm1Zhgn mutation (0 available); any Mldhr mutation (0 available)
Tg(GFAP-cre)25Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased glioblastoma incidence ( J:303725 )
• at 55-65 weeks of age

behavior/neurological
ataxia ( J:303725 )
• at 55-65 weeks of age
paralysis ( J:303725 )
• at 55-65 weeks of age
seizures ( J:303725 )
• at 55-65 weeks of age

nervous system
seizures ( J:303725 )
• at 55-65 weeks of age
increased glioblastoma incidence ( J:303725 )
• at 55-65 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory